Improving diagnostics and neurocognitive outcomes in HIV/AIDS-related meningitis (COAST) is an ongoing observational study conducted in Uganda. The overall objective is to determine the etiology and to improve long-term outcomes of Central-Nerve-System infections in Sub-Saharan Africa among adults with HIV. Participants receive standard of care therapy for their current meningitis illness, and are observationally followed up to 18 weeks after meningitis diagnosis, with optional annual follow-up thereafter.
Funder: National Institutes of Health, National Institute of Neurological Disorders and Stroke.