OraRad

OraRad: Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients is a six-center registry study documenting dental and other oral outcomes in individuals who receive external beam radiation therapy with curative intent as part of clinical care for head and neck cancer. Study participants receive a baseline oral examination before beginning radiation therapy with follow-up examinations at six-month intervals for up to two years after radiation therapy. The primary outcome is the two-year rate of tooth loss; secondary outcomes include measures of dental caries, periodontal health, salivary flow, and exposed bone/osteoradionecrosis. Enrollment finished in November 2017 with 572 participants being eligible for follow-up after receiving radiation therapy. Follow-up is likely to finish early in 2020.